Fifth disease pregnancy : Causes, Symptoms, and Treatments

fifth disease pregnancy

    Parvovirus B19 Infection, or Fifth Disease: Causes, Symptoms, and Treatments

    Parvovirus B19 infection, or "fifth disease," is primarily characterized by a rash. What are its symptoms? How is it treated?

    What is Parvovirus B19 infection or "fifth disease"?

    Viral infection caused by human parvovirus B19 is also called fifth disease, erythema infectiosum, or erythema infectiosum. It is a contagious, usually mild infection that occurs most frequently in late winter and early spring.

    It is most often characterized by the appearance of a rash, flu-like symptoms, and joint pain.

    How is Parvovirus B19 infection transmitted?

    This infection is transmitted through the respiratory tract by inhaling small droplets, viral particles released into the air by an infected person when they cough or sneeze. It can also be transmitted when someone touches a person or object contaminated by the virus and then puts their fingers in their mouth.

    More rarely, erythema infectiosum can also be transmitted through the bloodstream, particularly through blood transfusions.

    Symptoms of Parvovirus B19 Infection

    Symptoms of Parvovirus B19 infection are usually mild, and up to 25% of adults and children infected with the virus experience no symptoms.

    How does erythema epidermis manifest in children?

    Among children affected by the symptoms, the initial symptoms include reddening of the cheeks and a rash. This is specifically referred to as a "gloves and socks" papulo-purpuric rash, characterized by palpable blood flow under the skin on the extremities, accompanied by red patches of skin and painful swelling.

    "Don't panic when you see a rash. It often appears on the cheeks, legs, and arms and disappears spontaneously within 7 to 10 days of its onset."

    Symptoms may be more severe or intense in children with anemia or sickle cell disease.

    How does erythema infectiosum manifest in adults?

    Most adults have been immunized against the disease since childhood. When this is not the case, they may experience some symptoms.

    In 50% of cases, they, like children, may experience a rash.

    Children, like adults, infected with erythema infectiosum are contagious a few days before the appearance of this characteristic rash.

    Adults may also experience mild joint pain (non-erosive arthritis) and a feeling of swelling (in 70% of cases). These joint symptoms are particularly common in women (mainly in the hands, wrists, ankles, and knees).

    Headaches, sore throats, and stomach pain may also occur.

    The intensity of symptoms varies from person to person. However, some are more at risk than others.     These include:

  • People with autoimmune diseases, such as AIDS, type 1 diabetes, or multiple sclerosis
  • Pregnant women

    Parvovirus B19 infection during pregnancy

    The possibility of infection in pregnant women is quite low. However, if they do contract the disease, the virus can be transmitted from the mother to the fetus via transplacental passage. This can cause severe anemia in the fetus, which occurs in one-third of cases of primary infection in pregnant women.

    The risk of miscarriage is 13% in early pregnancy. Beyond 20 weeks of gestation, this risk does not exceed 1%. If the diagnosis is confirmed, clinical, immunological, and ultrasound (Doppler) monitoring will be initiated to look for signs of fetal distress throughout the course of the disease.

    "We will primarily look for signs of anemia, which will be manifested by fluid accumulation in the fetus (ascites) and/or the presence of edema." If this is the case, a transfusion will be administered directly into the uterus."

    Treatment and follow-up will depend on the stage of the pregnancy. "If the Parvovirus B19 infection causes complications late in the pregnancy, we will proceed with an early delivery and the baby will be cared for in the neonatology unit as a preterm baby. The baby will receive appropriate treatment."

    How can erythema multiforme be detected?

    When the symptoms listed above (fever, redness, joint pain) occur, it's best to have a blood test to confirm the diagnosis.

    It will detect - or not - Parvovirus B19 infection. If the test is positive for a pregnant woman, the doctor should be notified so that they can monitor the progression of symptoms. A PCR test can be performed on the amniotic fluid to determine whether the fetus has been affected or not.

    Treatment: How to treat infection caused by human parvovirus B19?
There is no treatment or vaccine for parvovirus B19 infection. It is up to the immune system to fight for recovery. However, attempts can be made to alleviate and relieve symptoms.

    "It is recommended to limit sun exposure as much as possible during the illness and to cut children's nails very short to prevent them from scratching and worsening their lesions." Hygiene measures, including intensive handwashing, can also help prevent the spread of the virus.

    Once a person has been infected with the virus, they are immune for life against future parvovirus B19 infections.

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